使用高分辩气相色谱法环糊精接枝聚硅氧烷 (二环〔2 ,6 二 O 戊基 3 O 己烯基 ( 5 )〕五环〔2 ,6 二 O 戊基 3 O 甲基〕 β 环糊精 聚硅氧烷 )作手性固定相 ,实现了α 羟基酮的有效拆分 ,并测定了一系列光学活性 3 羟基 2 丁酮的对映体过剩值 (e .e值 )。结果表明 ,所选取的手性固定相对测定此类不对称催化反应产物的光学产率 ,评价催化体系的手性选择性均具有较好的效果。 Cyclodextrin-grafted polysiloxane (bicyclo [2,6] dioxolane 3 O hexenyl (5)] pentacyclo [2,6] dioxolane 3 O methyl] β cyclodextrin polysiloxane) as a chiral stationary phase, the effective resolution of α-hydroxyketones was achieved and the enantiomeric excesses (e · e values) of a series of optically active 3-hydroxy 2-butanones were determined. The results show that the selected chiral stationary phase has good effect on the determination of the optical yield of such asymmetric catalytic reaction products and the evaluation of the chiral selectivity of the catalytic system.