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目的探讨微生态调节剂在急性重症胰腺炎治疗中的临床疗效。方法将48例患者随机分为试验组和治疗组,试验组给予传统治疗方法,而治疗组在给予传统治疗方法基础上加用美常安口服。结果两组患者在临床疗效上包括生化指标(血淀粉酶、血脂肪酶)恢复正常时间的比较及肠道菌群的变化,差异无统计学意义。但治疗组在加用美常安后白细胞恢复正常的时间较试验组缩短,胰腺感染例数减少,住院时间缩短,同时,双歧杆菌的数目明显增加,与试验组比较,差异有统计学意义。结论美常安能改善肠道屏障功能,减少感染等并发症的发生,调节肠道菌群失调。
Objective To investigate the clinical efficacy of microecological regulator in the treatment of acute severe pancreatitis. Methods 48 patients were randomly divided into experimental group and treatment group, the experimental group given traditional treatment methods, while the treatment group given the traditional treatment methods based on the use of the United States Changan oral. Results The two groups of patients in the clinical efficacy including biochemical indicators (blood amylase, lipase) to restore normal time comparison and changes in intestinal flora, the difference was not statistically significant. However, after treatment with MEBO, leukocytes returned to normal in the treatment group shortened as compared with the test group, the number of cases of pancreas infection was reduced, the hospitalization time was shortened, and the number of bifidobacteria significantly increased. Compared with the experimental group, the difference was statistically significant. Conclusions Mei Chang An can improve intestinal barrier function, reduce the incidence of complications such as infection and regulate intestinal flora.