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目的观察性传播疾病(STD)中单纯疱疹病毒Ⅱ型(HSV-Ⅱ)临床感染情况。方法对1 567例患有STD的患者进行泌尿生殖道分泌物HSV-ⅡDNA检测。结果1 567例STD患者中HSV-ⅡDNA阳性为398例占25.40%,其中男性阳性率26.60%(216/812),女性阳性率24.11%(182/755)。泌尿生殖道有明显溃疡的427例中HSV-ⅡDNA阳性320例阳性率74.94%,1 140例无溃疡中HSV-ⅡDNA阳性78例,阳性率6.84%。结论在STD感染患者中HSV-Ⅱ感染较为常见。泌尿生殖道无溃疡的STD患者中仍存在HSV-Ⅱ病毒的感染。荧光PCR技术检测HSV-Ⅱ感染有较好的临床应用价值,值得临床推广。
Objective To observe the clinical infection of herpes simplex virus type Ⅱ (HSV-Ⅱ) in sexually transmitted diseases (STD). Methods Genomic DNA of HSV-Ⅱ was detected in 1 567 STD patients. Results The positive rate of HSV-Ⅱ DNA in 1 567 STD patients was 25.40% (26.60%, 216/812). The positive rate of female was 24.11% (182/755). The positive rate of HSV-ⅡDNA in 427 cases with genitourinary tract ulceration was 74.94%, and the positive rate was 6.84% in 1140 cases of non-ulcer HSV-ⅡDNA. Conclusions HSV-Ⅱ infection is more common in patients with STD infection. HSV-II virus infection is still present in genitourinary tract-free STD patients. Fluorescent PCR detection of HSV-Ⅱ infection has a good clinical value, worthy of clinical promotion.