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目的:探讨左房内径(LAD)、血清尿酸(UA)水平与老年心房颤动的相关性。方法:选择2013年1月至2016年7月在我院住院的60岁以上的非瓣膜性房颤患者,共166例,其中持续性房颤组85例,阵发性房颤组81例,选择同期无房颤的高血压、冠心病老年患者83例作对照组。通过心脏彩超检查检测LAD、左心室舒张末期内径(LVDD)、左心室收缩末期内径(LVDS)、左心室射血分数(LVEF),以≥40 mm为左房内径增大。并采用生化分析检测患者血清UA水平。结果:(1)持续性房颤组LAD、LVEF、左心房增大发生率均显著高于阵发性房颤组和对照组,而阵发性房颤组以上指标均明显高于对照组,差异具有统计学意义(P<0.05)。(2)持续性房颤组和阵发性房颤组患者血清UA水平均显著高于对照组,但持续性房颤组和阵发性房颤组之间血清UA水平比较差异无统计学意义(P>0.05)。结论:左心房内径大小、血尿酸水平与老年患者心房颤动的发生密切相关。
Objective: To investigate the relationship between left atrium diameter (LAD), serum uric acid (UA) and senile atrial fibrillation. METHODS: A total of 166 patients with non-valvular AF who were hospitalized in our hospital from January 2013 to July 2016 were selected, including 85 patients with persistent AF and 81 patients with paroxysmal AF, Select the same period without atrial fibrillation of hypertension, coronary heart disease in 83 elderly patients as a control group. LAD, LVDD, LVDS and LVEF were detected by echocardiography, and the left atrial diameter was increased to ≥40 mm. Biochemical analysis was used to detect serum UA levels in patients. Results: (1) The incidences of LAD, LVEF and left atrial enlargement in patients with persistent AF were significantly higher than those in patients with paroxysmal atrial fibrillation and control group, while those in patients with paroxysmal atrial fibrillation were significantly higher than those in control group The difference was statistically significant (P <0.05). (2) Serum UA levels in patients with persistent atrial fibrillation and paroxysmal atrial fibrillation were significantly higher than those in control group, but there was no significant difference in serum UA levels between patients with persistent atrial fibrillation and those with paroxysmal atrial fibrillation (P> 0.05). Conclusion: The size of left atrial appendage and serum uric acid level are closely related to the occurrence of atrial fibrillation in elderly patients.