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目的评价布替萘芬和联苯苄唑治疗浅表真菌病的疗效和安全性。方法96例浅表真菌病患者随机分为布替萘芬乳膏组和联苯苄唑乳膏组,均分别涂搽患处,每日2次,体股癣及花斑癣疗程2周,手足癣疗程4周。结果疗程结束时布替萘芬乳膏组总有效率为91.7%,真菌清除率为87.5%,联苯苄唑乳膏组总有效率为83.3%,真菌清除率为83.3%,疗程结束2周后布替萘芬乳膏组总有效率为93.7%,真菌清除率为95.8%,联苯苄唑乳膏组总有效率为91.7%,真菌清除率为91.7%,两组均无不良反应。结论布替萘芬乳膏和联苯苄唑乳膏疗效和安全性比较差异无显著性(p>0.05)。“,” Objective To evaluate the butenafine and bifonazole treatment efficacy and safety of superficial mycosis .Methods 96 cases of superficial mycosis were randomly divided into butenafine cream group and bifonazole cream group ,were applied to the affected parts ,2 times a day ,tinea cruris and tinea versicolor tinea pedis treatment for 2 weeks ,4 weeks .Results at the end of the treatment of butenafine cream group ,the total effective rate was 91 .7% ,the fungal clearance rate was 87 .5% ,bifonazole cream group ,the total effective rate was 83 .3% ,the fungal clearance rate was 83 .3% ,the end of the treatment period of 2 weeks Houbu naphthalene Finn cream for group the total effective rate was 93 .7% ,the fungal clearance rate was 95 .8% ,biphenyl benzyl nitrate cream group ,the total effective rate was 91 .7% ,the fungal clearance rate was 91 .7% ,there were no adverse reactions in two groups .Conclusion the cloth is relatively naphthalene Finn cream for and bifonazole cream efficacy and safety of no significant difference (p>0 .05) .