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用早孕绒毛进行产前诊断正日益广泛开展。本文通过培养基加用Hepes液后,明显提高了分裂相出现率及可供分析率。用1%低渗构橼酸钠液,改善了染色体形态和分散状态。提出绒毛取材时间以孕6~7周最适宜。对10例染色体病风险急者做了产前诊断,认为孕早期绒毛产前诊断是可行、准确和安全的。
Prenatal diagnosis of early pregnancy villi is increasingly widespread. This article through the medium plus Hepes solution, significantly increased the appearance of the split phase and available for analysis. 1% low permeability sodium citrate solution to improve the chromosome morphology and dispersion. Put forward to take the time to 6 to 7 weeks of pregnancy the most appropriate. Prenatal diagnosis of 10 cases of risk of chromosomal risk prenatal diagnosis of villus prenatal diagnosis is feasible, accurate and safe.