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乳腺是粘膜相关淋巴瘤的发生部位，其原发淋巴瘤罕见。本文报导和分析了１４例乳腺原发性淋巴瘤的临床表现，形态特征和免疫表型。患者年龄范围为２６岁～６７岁，中位年龄４７岁。临床症状和体征除有乳腺肿块外．无其它特异性的阳性发现。病变部位包括左侧乳腺８例，右侧６例二组织学上均为弥漫型非何杰金氏淋巴瘤。１０个病例的免疫组化结果表明９例（９０．０％）为Ｂ细胞来源：１例（１０．０％）为Ｔ细胞来源。９个病例在组织学上可见淋巴细胞围绕残余乳腺导管浸润或导管上皮增生形成所谓淋巴上皮病变，部分瘤细胞有浆细胞样分化或瘤组织中有浆细胞浸润。提示至少部分肿瘤属粘膜相关淋巴瘤。结合文献对本病的诊断，治疗和预后作了简略地讨论。
The mammary gland is the site of the occurrence of mucosa-associated lymphoma, and its primary lymphoma is rare. This paper reports and analyzes the clinical manifestations, morphological features and immunophenotypes of 14 cases of primary breast lymphoma. The patient’s age ranged from 26 to 67 years, with a median age of 47 years. Clinical symptoms and signs in addition to breast lumps. No other specific positive findings. Lesions consisted of 8 cases of left breast and 6 cases of diffuse non-Hodgkin’s lymphoma. The immunohistochemical results of 10 cases showed that 9 cases (90.0%) were B cell sources: 1 case (10.0%) was the source of T cells. Histologically, 9 cases showed lymphocytes around the residual breast duct infiltrating or ductal hyperplasia forming so-called lymphoepithelial lesions. Some of the tumor cells had plasma cell-like differentiation or plasma cell infiltration in the tumor tissue. It is suggested that at least part of the tumor is a mucosa-associated lymphoma. Combined with the literature, the diagnosis, treatment and prognosis of this disease are briefly discussed.