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Objective To investigate the role of endoplasmic reticulum stress(ERS)-mediated apoptosis in athero-scle-rotic calcification of diabetic apolipoprotein E gene knocked-out(ApoE~(-/-))mice.Methods 6-week old male ApoE~(-/-) mice were first rendered diabetic by intraperitoneal injection of streptozotocin(STZ)for 5 days
Objective To investigate the role of endoplasmic reticulum stress (ERS) -mediated apoptosis in athero-scle-rotic calcification of diabetic apolipoprotein E gene knocked-out (ApoE ~ (- / -)) mice. Methods 6-week old male ApoE ~ - / -) mice were first rendered diabetic by intraperitoneal injection of streptozotocin (STZ) for 5 days