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目的:通过监测临床危急值提高药品不良反应(ADR)的上报质量。方法:分析临床药物治疗与出现临床危急值之间的联系,确定可疑的ADR病例。结果:调查中共发现23例疑似ADR报告,占调查期间总上报ADR例数的24.73%;主要ADR表现为血小板减少(13例),其次是尿素升高(5例);给药途径主要为静脉滴注(涉及21例),涉及品种以抗菌药物为主。结论:通过加强对临床危急值的监测,可以提高ADR的报告的质量,减少ADR的漏报率。
Objective: To improve the reporting quality of adverse drug reaction (ADR) by monitoring the clinical critical value. Methods: To analyze the relationship between clinical drug therapy and clinical emergencies, and to identify suspicious ADR cases. RESULTS: Twenty-three cases of suspected ADR were found in the survey, accounting for 24.73% of the total reported cases of ADR during the survey. The main manifestations of ADR were thrombocytopenia (13 cases), followed by elevated urea (5 cases) Instillation (involving 21 cases), involving varieties to antibacterial drugs. Conclusion: By monitoring the clinical critical value, we can improve the quality of ADR report and reduce the false negative rate of ADR.