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妊娠期母体免疫系统允许胎儿在子宫内生长发育直至分娩,迄今人们对其调节机理并未弄清.近年,随着免疫学的迅速发展,特别是免疫学新方法新技术在生殖免疫学领域中的应用,人们已观察到妊娠母体及母体-胎盘界面局部免疫系统在结构和功能方面的明显变化,发现了许多与这些变化有关的调节物质,并提出了种种可能的妊娠免疫调节机理.本文拟简述近年关于妊娠免疫调节物质及其凋节机理的研究进展.
In recent years, with the rapid development of immunology, especially the new immunological methods and new technologies in the field of reproductive immunology in the field of pregnancy, maternal immune system allows the fetus to grow and develop in the womb until delivery, , We have observed the obvious structural and functional changes of the local immune system at the maternal-maternal-placental interface and found many regulatory substances related to these changes and proposed various possible mechanisms of pregnancy immune regulation. In recent years, the research progress of immunomodulatory substances in pregnancy and its mechanism of apoptosis were briefly reviewed.