论文部分内容阅读
应用免疫组化方法观察了30例肾母细胞瘤组织中ras癌基因P~21蛋白和表皮细胞生长因子受体(EGFr),发现P~21蛋白主要在间叶细胞表达。EGFr阳性细胞在间叶细胞和肾小管上皮型细胞中多见,且以上皮型细胞呈强阳性染色。结果提示肾母细胞瘤组织细胞学和基因蛋白水平表达的多样性。
Immunohistochemistry was used to observe the expression of the oncogene P-21 and epidermal growth factor receptor (EGFR) in 30 nephroblastoma tissues. The results showed that the P-21 protein was mainly expressed in mesenchyme. EGFr positive cells in mesenchymal cells and tubular epithelial cells more common, and the epithelial cells were strongly positive staining. The results suggest the diversity of cytogenetics and gene protein expression in nephroblastoma tissue.