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应用光镜、电镜、细胞生长曲线和同位素技术等方法，研究了大鼠腹腔肥大细胞（ＰＭＣ）及ＰＭＣ上清（含ＰＭＣ释放的介质）对培养的同源肺成纤维细胞（ＬＦｂ）生长的影响。结果表明，实验组ＬＦｂ呈复层生长，Ｈ－ＴｄＲ掺入量和细胞密度均明显大于对照组（Ｐ＜０．００１）。提示ＰＭＣ释放的活性介质可能含有促进ＬＦｂ增生的因子。
The effects of peritoneal mast cells (PMC) and supernatant of PMC (medium containing PMC release) on the growth of cultured lung fibroblasts (LFb) were studied by light microscopy, electron microscopy, cell growth curve and isotope techniques. influences. The results showed that LFb in the experimental group grew in multiple layers, and the amount of H-TdR incorporation and cell density were significantly higher than that of the control group (P <0.001). This suggests that the active mediator released by PMC may contain factors that promote the proliferation of LFb.