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目的探讨川崎病的临床特点。方法对2001年6月至2009年1月住院治疗的56例川崎病病例进行回顾性分析。结果符合川崎病诊断标准的6项主要表现者28例(50%);符合5项主要表现者21例(37.5%);符合4项表现者6例(10.7%);有1例(1.8%)患儿病程中仅有发热,而无川崎病其它主要临床表现;合并冠状动脉病变27例(64.3%)。治愈:本组患者治愈48例,好转7例,自动出院1例,无死亡病例。除自动出院者外,所有病例均随访3个月至3年,冠脉扩张<4mm者均在3个月内恢复正常,4~7mm者约在6个月恢复正常,其中1例冠脉扩张9mm者仍在随访中。结论大多数川崎病患者症状较典型,可明确诊断,大剂量丙种球蛋白治疗效果较好。不完全性川崎病冠状动脉病变发生率高,临床应重视早期诊断和早期治疗。
Objective To explore the clinical features of Kawasaki disease. Methods A retrospective analysis of 56 cases of Kawasaki disease hospitalized from June 2001 to January 2009 was conducted. RESULTS: Six of the six major performers, who met the diagnostic criteria of Kawasaki disease, were 28 (50%), 21 (37.5%) were consistent with the five major manifestations, 6 (10.7%) were consistent with the four manifestations, ) Children had only fever in the course of their disease without other major clinical manifestations of Kawasaki disease; 27 cases had coronary artery lesions (64.3%). Cure: The group of patients cured in 48 cases, improved in 7 cases, 1 case of spontaneous discharge, no deaths. All patients were followed up for 3 months to 3 years except those who were discharged automatically. Those who had coronary artery dilatation <4 mm returned to normal within 3 months, and those with 4-7 mm returned to normal within 6 months. One case of coronary artery dilatation 9mm are still under follow-up. Conclusion Most patients with Kawasaki disease symptoms are typical, can confirm the diagnosis, high-dose gamma globulin treatment is better. Incomplete Kawasaki disease high incidence of coronary artery disease, clinical should pay attention to early diagnosis and early treatment.