论文部分内容阅读
熟知,癌症是人类尚未征服的最危险的致命疾病之一,近年人们都致力于攻克这一难关,并已研究出一些早期诊断的方法与治疗的药物。具有醌式结构的阿霉素(Adriamycin,简称AQ)为其中颇为有效的抗癌药物之一。但AQ对心脏有较强的损伤作用,致使其临床应用有很大局限。对AQ损伤心肌过程的初步研究显示:AQ诱导产生的活性氧自由基能损伤心肌线粒体,同时还提出利用自由基清除剂来弥补这一损伤。实验证明,五味子酚对阿霉素引
It is well-known that cancer is one of the most dangerous and deadly diseases human beings have not conquered. In recent years, people are all dedicated to tackling this difficult problem and have developed some early diagnosed methods and treatments. Quinone structure of Adriamycin (Adriamycin, referred to as AQ) is one of the more effective anti-cancer drugs. But AQ has a strong heart injury, resulting in its clinical application is very limited. Preliminary studies on the process of AQ injury to the myocardium showed that reactive oxygen species produced by AQ can damage myocardial mitochondria, and at the same time, it is proposed to use free radical scavengers to make up for this damage. Experiments show that schisandrin of doxorubicin cited