目的探讨可切除肝癌术前经肝动脉化学药物栓塞对肝切除手术的影响。方法回顾分析了自 1996年 1月至 1997年 1月收治的 12 6例患者 ,术前经肝动脉化学药物栓塞组 (TACE组 )6 2例 ,术前未经肝动脉化学药物栓塞组 6 4例。对比 2组手术前后肝功能指标变化 ,手术所见 ,肝门阻断时间 ,术中平均出血量 ,平均手术时间 ,术后 1、2、3d腹腔引流量 ,手术死亡率及并发症发生情况。结果 2组手术前后肝功能改变无差异 ,2组均无手术死亡。手术中发现术前TACE组胆囊壁增厚、萎缩、粘连及癌灶与膈肌、侧腹壁和网膜粘连远比非TACE组多。TACE组肝硬化加重 ,手术时间延长 ,术中失血量及术后 1、2、3d腹腔引流量多 ,2组之间手术并发症差异无显著意义。结论术前TACE使手术难度及危险性增加 ,对可切除肝癌术前进行TACE应持慎重态度 Objective To investigate the effect of preoperative hepatic artery chemoembolization on hepatectomy for resectable hepatic carcinoma. Methods A retrospective analysis was performed on 126 patients admitted from January 1996 to January 1997 in which 62 patients underwent transcatheter hepatic arterial chemoembolization (TACE group) and 6 4 patients who underwent preoperative hepatic arterial chemoembolization example. The changes of liver function indexes before and after operation were compared between the two groups. Surgical findings, hepatic portal vein occlusion time, average intraoperative blood loss, average operation time, postoperative 1, 2 and 3 d drainage, operative mortality and complications were compared. Results There was no difference in liver function between the two groups before and after surgery. No operative death occurred in both groups. Surgery found that preoperative TACE group gallbladder wall thickening, atrophy, adhesions and foci and diaphragm, side abdominal wall and omentum adhesion than non-TACE group more. TACE group increased liver cirrhosis, surgery time, intraoperative blood loss and abdominal drainage volume 1,2,3d after surgery, no significant difference in the surgical complications between the two groups. Conclusions Preoperative TACE increases the difficulty and risk of operation, and should take a cautious attitude on preoperative TACE for resectable liver cancer