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作者用胃癌组织匀浆免疫家兔制得了一个新的胃癌相关抗原的抗血清,对其相应抗原进行了初步的免疫学、免疫化学以及临床病例的研究。该抗原存在于胃癌组织、胃癌病人体液以及胚胎某些器官内,不是CEA和αFP或其他已报导的胃癌相关抗原。临床检测胃癌病人血清的阳性率82.1%(23/28),正常人阳性率0%(0/76),其他肿瘤也有不同程度的阳性率。检测血中该抗原,可作为胃癌辅助诊断或普查的一个指标,对胃癌患者外科手术予后的观察也有一定的价值。
The authors prepared a new anti-sera of gastric cancer-associated antigen by immunizing rabbits with homogenate of gastric cancer, and carried out preliminary immunological, immunochemical and clinical case studies of the corresponding antigens. The antigen is present in gastric cancer tissues, body fluids of gastric cancer patients, and certain organs of embryos, not CEA and αFP or other reported gastric cancer-associated antigens. The positive rate of serum in patients with gastric cancer was 82.1% (23/28), and the positive rate in normal people was 0% (0/76). Other tumors also had positive rates in different degrees. The detection of this antigen in blood can be used as an indicator for assisted diagnosis or screening of gastric cancer. It also has a certain value for the observation of gastric cancer after surgery.