Th9细胞是近年来发现的一种新型效应T细胞亚群,此类细胞以分泌IL-9和IL-10为典型特征,不同于已知的Th1、Th2、Th17和Treg,其专一性转录因子至今不甚明了。鉴于近年有关Th9细胞的新进展,本文就可能参与Th9细胞分化的转录因子及该类细胞分化的可塑性问题作简要综述。 Th9 cells are a novel subset of effector T cells discovered in recent years. These cells are characterized by the secretion of IL-9 and IL-10, which are different from the known Th1, Th2, Th17 and Tregs, and their specific transcription The factor is not clear until now. In view of the new progress of Th9 cells in recent years, we briefly reviewed the transcription factors that may participate in Th9 cell differentiation and the plasticity of these cell types.