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目的:探究奥美拉唑与克拉霉素联合治疗69例慢性胃炎的疗效。方法:对照组予以单纯奥美拉唑治疗,观察组在此基础上联合克拉霉素治疗,观察对比两组临床疗效、用药安全性及病情复发情况。结果:观察组临床总有效率为95.7%,明显高于对照组的79.7%(P<0.05);观察组药物不良反应发生率为8.7%,对照组药物不良反应发生率为5.8%,比较无统计学意义(P>0.05);随访6个月,观察组复发率为4.5%,明显低于对照组的14.5%(P<0.05)。结论:奥美拉唑联合克拉霉素治疗慢性胃炎的临床疗效确切,病情复发率较低,且用药安全可靠。
Objective: To investigate the efficacy of omeprazole and clarithromycin in the treatment of 69 cases of chronic gastritis. Methods: The control group was treated with omeprazole alone, and the observation group was treated with clarithromycin. The clinical efficacy, drug safety and relapse were observed and compared. Results: The total clinical effective rate in the observation group was 95.7%, significantly higher than that in the control group (79.7%, P <0.05). The adverse drug reaction rate in the observation group was 8.7% and that in the control group was 5.8% The recurrence rate was 4.5% in the observation group, which was significantly lower than that in the control group (14.5%, P <0.05). Conclusion: The combination of omeprazole and clarithromycin in the treatment of chronic gastritis has definite curative effect, lower relapse rate and safe and reliable medication.