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目的：探讨并分析米非司酮用于治疗子宫肌瘤的效果。方法：从2011年10月至2012年12月就诊于我院的子宫肌瘤患者中随机选取50例，每日口服12.5m g的米非司酮，连续服用3个月，治疗前与治疗后均利用彩色超声对患者的子宫及肌瘤的体积进行检测，在实验室中观察患者的肝功能、血常规以及尿常规。结果：50例患者在治疗过程中均有闭经现象，痛经及下腹坠胀感的症状消失，贫血有所缓解。子宫肌瘤的体积明显缩小，有统计学意义(P<0.01)。结论：采用米非司酮来进行子宫肌瘤的治疗具有较好的效果，且治疗过程中的不良反应少，治疗后的复发率也较低，值得应用与推广。“,”Objective: To investigate and analyze the effect of mifepristone in the treatment of uterine fibroids. Methods: from 2011 October to 2012 December in our hospital for treatment of uterine myoma patients were randomly selected 50 cases, a daily dose of 12.5mg of mifepristone, continuous take 3 months, before and after the treatment were utilized volume color Doppler ultrasound in uterus and myoma were detected, in the laboratory observation in patients with liver function, blood and urine routine. Results: 50 patients were in the treatment of amenorrhea, dysmenorrheal and abdominal bulge symptoms disappear, anemia eased. Uterine fibroid volume was significantly reduced, with statistical significance (P < 0.01). Conclusion: the treatment of mifepristone has better effect for uterine fibroids, and the treatment of adverse reactions in the process of low, treatment of the recurrence rate is low, it is worth of application and promotion.