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目的:分析对比阿奇霉素分别用口服和静脉的方法治疗小儿支原体肺炎的临床效果和安全性。方法:选取我院在2016年2月-10月治疗的60名小儿支原体肺炎的患儿,将他们随机分为对照组和研究组,两组各30名,其中对照组患儿采取静脉注射阿奇霉素的方法进行治疗,研究组采取口服阿奇霉素的方法进行治疗。治疗结束后对比分析两组临床效果。结果:治疗完成后研究组患儿的治疗有效率和对照组的无较大差别,差异不具有统计学意义,研究组患儿的不良反应发生率要显著低于对照组,差异具有统计学意义。结论:对小儿支原体肺炎患儿采取口服和静脉注射阿奇霉素的方法治疗后临床疗效没有明显的差异,采用口服的方法不良反应发生率较低,安全性较高,值得在临床上广泛应用。
OBJECTIVE: To analyze the clinical efficacy and safety of azithromycin against oral mycoplasma pneumonia by oral and intravenous methods. Methods: Sixty children with mycoplasma pneumonia were treated in our hospital from February to October in 2016. They were randomly divided into control group and study group, with 30 in each group. The control group received intravenous azithromycin Method of treatment, the study group to take oral azithromycin treatment. After treatment, the clinical effects of two groups were compared. Results: There was no significant difference between the treatment group and control group after treatment, the difference was not statistically significant, the incidence of adverse reactions in study group was significantly lower than that in control group, the difference was statistically significant . Conclusion: There is no significant difference in the clinical efficacy of azithromycin in children with mycoplasma pneumonia after oral and intravenous injection. Adopting oral method, the incidence of adverse reactions is low and the safety is high, so it is worth to be widely used clinically.