兹报告一例应用HBsAg iRNA引起重型肝炎:患者男,28岁,1982年7月曾患急性黄疸型肝炎住我院56天临床治愈出院。同年10月28日因乏力、肝区痛伴肝功异常再入院。体检:巩膜、皮肤无黄染,无蜘蛛痣和肝掌,心肺(-),肝脾未及,腹部未及包块,腹水症(-)。化验:血、尿、粪常规正常,TSB1.3mg/dl,TTT、TFT正常,SGPT75u,AKP16u,CHE66u,γ-GT63u,A/G 4.0/2.4,血清蛋白电 We report a case of severe hepatitis caused by HBsAg iRNA: male, 28 years old, had acute jaundice hepatitis in July 1982 live in our hospital for 56 days clinical cure and discharge. October 28 the same year due to fatigue, liver pain and liver abnormalities re-admitted. Physical examination: sclera, skin without yellow dye, no spider nevus and liver palms, cardiopulmonary (-), liver and spleen not yet, abdomen and mass, ascites (-). Laboratory: blood, urine, normal feces, TSB1.3mg / dl, TTT, normal TFT, SGPT75u, AKP16u, CHE66u, γ-GT63u, A / G 4.0 / 2.4, serum protein electricity