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目的:了解子宫肌瘤、输卵管妊娠、不孕、死胎和胎儿畸形妇女人巨细胞病毒(HCMV)近期感染状况。方法:采用酶联免疫吸附试验(ELISA)对370例子宫肌瘤、310例输卵管妊娠、78例不孕、61例死胎和33例胎儿畸形共852例妇女的静脉血标本进行了HCMV-IgM检测,同时以120名孕前检查的健康妇女为对照。结果:在子宫肌瘤、输卵管妊娠、不孕、死胎、胎儿畸形妇女中,分别检测出HCMV-IgM阳性标本10例、6例、2例、4例和6例,阳性率分别为2.70%、1.94%、2.56%、6.56%和18.18%,巨细胞病毒近期感染率,在上述各组妇女中,以胎儿畸形组最高,死胎组次之;在120名健康妇女中未检测出HCMV-IgM阳性标本,感染率为0。结论:孕妇感染HCMV是导致胎儿畸形和死胎的原因之一。
Objective: To investigate the recent infection status of human cytomegalovirus (HCMV) in uterine fibroids, tubal pregnancy, infertility, stillbirth and fetal malformations. Methods: HCMV-IgM was detected by ELISA in 852 women with uterine fibroids, 310 cases of tubal pregnancy, 78 cases of infertility, 61 cases of stillbirth and 33 cases of fetal malformations At the same time, 120 healthy pregnant women before pregnancy test were taken as controls. Results: The positive samples of HCMV-IgM were detected in 10 cases, 6 cases, 2 cases, 4 cases and 6 cases in uterine fibroids, tubal pregnancy, infertility, stillbirth and fetus malformation. The positive rates were 2.70% 1.94%, 2.56%, 6.56% and 18.18%. The recent infection rates of cytomegalovirus were the highest in fetal malformation group and the stillbirth group among the above-mentioned groups of women; HCMV-IgM was not detected in 120 healthy women Specimens, infection rate is 0. Conclusion: HCMV infection in pregnant women is one of the causes of fetal malformation and stillbirth.