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目的探讨舌下含服米索前列醇用于人工流产术的临床效果。方法将120例自愿要求进行人工流产的早期妊娠患者随机分为观察组(米索前列醇舌下含服)和对照组(常规人工流产),每组60例。对2组扩宫情况、术中疼痛、子宫收缩幅度、子宫出血量、副反应发生情况等进行比较。结果试验组较对照组宫颈明显松弛(P<0.01),宫缩幅度显著增强(P<0.05),术中出血明显减少。2组均未发生人流综合征。结论米索前列醇舌下含服后行人工流产术,宫颈松弛良好,术中疼痛轻,且使用方便、安全,适合临床推广。
Objective To investigate the clinical effect of sublingual misoprostol for artificial abortion. Methods A total of 120 early pregnancy patients who voluntarily requested abortion were randomly divided into observation group (misoprostol sublingual group) and control group (conventional induced abortion), 60 cases in each group. On the 2 groups of expansion of the situation, intraoperative pain, uterine contraction amplitude, uterine bleeding, the incidence of side effects were compared. Results Compared with the control group, the cervix in the experimental group was significantly saggy (P <0.01), and the contractile amplitude was significantly increased (P <0.05). The intraoperative bleeding was significantly reduced. No flow-induced syndrome occurred in both groups. Conclusion Misoprostol sublingual treatment of artificial abortion, good cervical relaxation, intraoperative pain, and easy to use, safe, suitable for clinical promotion.