目的 探索和评价经导管堵闭术在先天性心脏病治疗中的价值。方法 用Amplatzer堵闭器对12例光天性心脏病患者在局麻或全麻下经导管进行堵闭术,其中室间隔缺损6例,房间隔缺损4例,动脉导管未闭2例。结果 12例患者堵闭1次成功,心脏杂音消失,术后6～12 h下床活动,4～6d痊愈出院。结论 用Amplatzer堵闭器经导管堵闭部分先天性心脏病,创伤小、操作简便、效果好,是一种值得推广的方法。 Objective To explore and evaluate the value of transcatheter closure in the treatment of congenital heart disease. Methods Amplatzer was used to block 12 patients with APD under catheterization or general anesthesia. Among them, 6 cases were ventricular septal defect, 4 cases were atrial septal defect and 2 cases were patent ductus arteriosus. Results 12 patients successfully blocked one time, heart murmur disappeared, 6 ~ 12 h after bed activity, 4 ~ 6d healed and discharged. Conclusions Transcatheter closure of some congenital heart disease with Amplatzer blocker is less invasive and easier to operate. It is a worthy promotion method.