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目的探讨鼻NK/T细胞淋巴瘤的临床特征、治疗效果和预后。方法对12例鼻NK/T细胞淋巴瘤患者按Ann Arbor-Cotswolds分期方案进行临床分期,12例分别采用化疗、放疗和两者结合等方法治疗。结果12例鼻NK/T细胞淋巴瘤局部病变主要表现弥漫性黏膜溃疡、坏死,而非结节状增生,10例死亡,2例健在。结论鼻NK/T细胞淋巴瘤好发部位为鼻甲和鼻中隔,好发于男性,病程较短,临床进展快速,治疗效果不满意,具有较高的恶性度,预后较差。
Objective To investigate the clinical characteristics, therapeutic effect and prognosis of nasal NK / T cell lymphoma. Methods The clinical stage of Ann Arbor-Cotswolds staging was evaluated in 12 patients with nasal NK / T cell lymphoma. Twelve patients were treated with chemotherapy, radiotherapy and combination therapy respectively. Results Twelve patients with nasal NK / T cell lymphoma mainly showed diffuse mucosal ulceration and necrosis, but not nodular hyperplasia. Ten patients died and two patients were alive. Conclusions Nasal NK and T-cell lymphoma are nasal turbinates and nasal septum. Occur in nasal and nasal septum, which occurs in males. The course of the disease is short, the clinical progress is rapid, the treatment effect is not satisfied, the malignant degree is high, and the prognosis is poor.