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非甲非乙型肝炎的传染源包括急、慢性患者和病毒携带者,尤以慢性非甲非乙型肝炎患者更为重要。传播途径经皮肤传播主要为输血、血制品及注射。在美国输血后肝炎中85～95%为非甲非乙型肝炎。在血制品中,以Ⅷ和Ⅸ凝血因子浓缩制品引起的传播最常见,西方国家注射毒品引起非甲非乙型肝炎也很重要。在注射毒品者发生的急性肝炎中,约25～50%属于非甲非乙型肝炎。此外,血液透析、器官移植、外科手术等也可传播非甲非乙型肝炎。
Sources of non-A, non-B hepatitis include acute and chronic patients and carriers of the virus, especially in patients with chronic non-A, non-B hepatitis. The main routes of transmission through the skin for blood transfusion, blood products and injection. In the United States 85 to 95% of post-transfusion hepatitis is non-A, non-B hepatitis. In blood products, the most common cause of transmission due to concentrated preparations of VIII and IX coagulation factors is also important in western countries in injecting drug-induced non-A, non-B hepatitis. About 25-50% of acute hepatitis in drug-injecting patients are non-A, non-B hepatitis. In addition, hemodialysis, organ transplantation, surgery and the like can also transmit non-A, non-B hepatitis.