论文部分内容阅读
目的分析北京市海淀区2012年疑似预防接种异常反应(adverse events following immunization,AEFI)的发生特征,评价海淀区AEFI监测系统运转情况。方法通过AEFI信息管理系统,收集2012年报告的AEFI,采用描述性方法进行流行病学分析。结果 2012年海淀区共报告AEFI个案174例,报告发生率12.0/10万,一般反应报告率为6.4/10万,48 h内报告率和调查率均为100%。AEFI报告个案中≤2岁占82.2%,男、女比例为1.24:1,多发生在接种后24 h,没有明显的季节聚集性。反应分类一般反应占53.5%,异常反应占31.0%,偶合症占15.5%。一般反应以接种百白破后发热/红肿/硬结发生率最高(38.2/10万),异常反应以接种7价肺炎疫苗过敏性皮疹发生率最高(53.3/10万)。结论海淀区AEFI监测敏感性和及时性较高,但仍需进一步加强一般反应监测。
Objective To analyze the occurrence characteristics of suspected AEFI in Haidian District in 2012 and evaluate the operation of AEFI monitoring system in Haidian District. Methods AEFI was collected through the AEFI information management system and reported in 2012 using a descriptive approach for epidemiological analysis. Results A total of 174 cases of AEFI were reported in Haidian District in 2012, with a reported incidence of 12.0 / 100000, a general response rate of 6.4 / 100000 and a reported rate of 100% within 48 hours. In the AEFI case, ≤2 years old accounted for 82.2%, male and female ratio was 1.24: 1, occurred 24 hours after inoculation, there was no obvious seasonal aggregation. Response classification General reaction accounted for 53.5%, abnormal reaction accounted for 31.0%, 15.5% of coupling syndrome. In general, the incidence of fever / inflame / induration was the highest (38.2 / 100000) after inoculation of daphnia and the highest incidence was (53.3 / 100000) of anaphylactic allergic rash with abnormal reaction to vaccination with 7-valent pneumonia vaccine. Conclusion The sensitivity and timeliness of AEFI surveillance in Haidian are high, but the general reaction monitoring still needs to be further strengthened.