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虽然 C群脑膜炎球菌结合疫苗已纳入英国婴儿免疫接种程序 ,但目前尚无有效的疫苗解决 B群感染问题。然而 Por A外膜蛋白 (OMP)诱导的特异性抗体与杀菌活性存在关联使 Por A成为 B群脑膜炎球菌疫苗潜在的候选物。本文评价了六价 Por A外膜囊(OMV)疫苗的效力。 六价 Por A OMV
Although the group C meningococcal conjugate vaccine has been included in the UK infant immunization program, there is currently no effective vaccine to address the issue of group B infection. However, the association of Por A outer membrane protein (OMP) -induced specific antibodies with bactericidal activity makes Por A a potential candidate for serogroup B meningococcal vaccines. This article reviews the efficacy of the hexavalent Por A Outer Membrane Vesicle (OMV) vaccine. Six-price Por A OMV