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为观察畸变产物耳声发射（ＤＰＯＡＥ）对侧抑制效应的临床应用价值。方法：研究以白噪声为对侧声刺激，对１７例正常人（３４耳），１３例蜗性聋（１３耳），９例蜗后聋（９耳）进行了ＤＰＯＡＥ及其对测抑制效应测试。结果：蜗性聋耳的ＤＰＯＡＥ幅值较正常耳显著下降（Ｐ＜０．０１），对侧抑制效应减弱，但与正常人差异无统计学意义（Ｐ＞０．０５）。蜗后聋耳ＤＰＯＡＥ幅值高于正常耳（Ｐ＞０．０５），对侧抑制效应显著减弱（Ｐ＜０．０１）或消失、或不但不抑制反而使ＤＰＯＡＥ幅值增加。结论：蜗后聋耳的ＭＯＣＳ功能紊乱或障碍。ＤＰＯＡＥ及其对侧抑制效应测试有助于感音神经聋的鉴别诊断，对蜗后聋更有独特的诊断意义，因此有重要的临床应用价值。
To observe the clinical application value of the contralateral product of distortion product otoacoustic emissions (DPOAE). Methods: To investigate the inhibitory effect of DPOAE on contralateral hearing loss in 17 normal subjects (34 ears), 13 cases of cochlear deafness (13 ears) and 9 cases of cochlear deafness (9 ears) test. Results: The amplitude of DPOAE in cochlear deafness ears was significantly lower than that in normal ears (P <0.01), while the contralateral inhibitory effect was weakened, but there was no significant difference with normal subjects (P> 0.05). The amplitude of DPOAE in the deafed ears was higher than that in the normal ears (P> 0.05), and the contralateral inhibitory effect was significantly weakened (P <0.01) or disappeared, or DPOAE amplitude was increased. Conclusions: MOCS dysfunction or disturbance in deaf ears. DPOAE and its contralateral inhibitory effect test contribute to the differential diagnosis of sensorineural hearing loss, which has more unique diagnostic significance for cochlear deafness and therefore has important clinical value.