庆大霉素在临床已广泛应用,著者用20只豚鼠作动物实验以观察庆大霉素对末梢前庭感觉器官的毒性作用。著者将豚鼠分为四组,每组5只,以250毫克/公斤剂量的庆大霉素硫酸盐注射入豚鼠腹腔,分别连续注射5、10、15、30天。末次注射一周后取出动物内耳,经固定、铺片、银反应及琥珀脱氢酶染色后,光学显微镜检查,可以见到以下变化: Gentamycin has been widely used in clinical practice, the author used 20 guinea pigs for animal experiments to observe the toxic effects of gentamicin on the peripheral vestibular sensory organs. The authors divided the guinea pigs into four groups of five with 250 mg / kg gentamycin sulphate injected into the peritoneal cavity of guinea pigs for consecutive 5, 10, 15 and 30 days. One week after the last injection, the animal’s inner ear was taken out, and the following changes were observed after fixation, spreading, silver reaction and amber dehydrogenase staining and optical microscopy: