【摘 要】
：
An efficient synthesis of 3,4 dihydropyrimidinones from aldehyde, β keto ester and urea in ethanol using cobalt chloride hexahydrate or lanthanum chlorid
【出 处】
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Chinese Journal of Chemistry
论文部分内容阅读
An efficient synthesis of 3,4 dihydropyrimidinones from aldehyde, β keto ester and urea in ethanol using cobalt chloride hexahydrate or lanthanum chloride heptahydrate as a catalyst was described. Compared to the classical Biginelli reaction, this new method consistently has the advantage of good yields (56%-99%) as well as short reaction time (4-5 h).
An efficient synthesis of 3,4 dihydropyrimidinones from aldehyde, β keto ester and urea in ethanol using cobalt chloride hexahydrate or lanthanum chloride heptahydrate as a catalyst was described. Compared to the classical Biginelli reaction, this new method consistently has the advantage of good yields ( 56% -99%) as well as short reaction time (4-5 h).
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