许多文献已报道亚硒酸盐对甲基汞的神经毒性具有拮抗作用。但最近Lee等报道了亚硒酸盐对甲基汞引起小鼠腭裂并无防止效果,这提示甲基汞的神经毒性作用和致畸作用的机理可能不同。文献中也报道了肾上腺皮质激素能引起小鼠腭裂。因此,甲基汞除其特有的神经毒性外,它可能是一种全身应激因子,使血浆 It has been reported in many literature that selenite has an antagonistic effect on the neurotoxicity of methylmercury. Recently, however, Lee et al. Reported that selenite did not prevent methylmercury-induced cleft palate in mice, suggesting that the mechanism of neurotoxicity and teratogenicity of methylmercury may be different. It has also been reported in the literature that adrenal cortex hormones cause cleft palate in mice. Therefore, methylmercury in addition to its unique neurotoxicity, it may be a systemic stress factor, plasma