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目的:评价经皮经腔间隔消融术 (PTSMA)治疗肥厚型梗阻性心肌病 (HOCM)疗效。 方法:用心导管对 3例HOCM患者行 PTSMA术 ,分别于术前及术后 3个月、1年、2年用超声心动图测量左室流出道压力阶差 (L VOGT)、室间隔厚度 (IVST)、左室流出道宽度 (L VOT)、射血分数 (EF)值 ,并观察临床表现。 结果:随访 2年 ,患者 L VOGT、IVST值均有所下降 ,L VOT增加 ,临床症状基本缓解 ,心功能恢复至 ～ 级 ,心脏杂音降至 ～ 级。结论 :PTSMA能显著降低 L VOGT及 IVST、增加 L VOT,可将其作为难治性 HOCM的一种有效治疗方法
Objective: To evaluate the efficacy of percutaneous transluminal ablation (PTSMA) in the treatment of hypertrophic obstructive cardiomyopathy (HOCM). Methods: PTSMA was performed in 3 HOCM patients by cardiac catheterization. Left ventricular outflow tract pressure gradient (L VOGT), interventricular septum thickness ( IVST), left ventricular outflow tract width (L VOT), ejection fraction (EF), and observed the clinical manifestations. Results: After 2 years of follow-up, the values of L VOGT and IVST decreased, L VOT increased, the clinical symptoms were basically relieved, the cardiac function recovered to ~ level, and the heart murmur dropped to ~ level. Conclusion: PTSMA can significantly reduce L VOGT and IVST and increase L VOT, which can be used as an effective treatment for refractory HOCM