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乙型肝炎表面抗原(HBsAg)阳性母亲所生的婴儿,也常有乙型肝炎病毒(HBV)感染。许多这种新生儿将成为慢性HBV的携带者。其中约1/4在其后将发展成肝硬变或肝细胞性肝癌。此种围产期的感染能通过新生儿的免疫予以预防。本文并推荐对高危婴儿的处理方法。 HBsAg的母亲如果也是乙型肝炎e抗原(HBeAg)阳性时,则她所生的婴儿约90％发生围产感染。母亲是HBeAg阴性或她们对HBeAg有抗体,其婴儿有较少的危险,但仍能受感染。受感染的婴儿通常要在生后几周才变成HBsAg阳性。虽然他们发生黄疸或急性肝炎是罕见的,但转氨酶水平的升高则常见。因为他们是持
Babies born to mothers with hepatitis B surface antigen (HBsAg) are also often infected with hepatitis B virus (HBV). Many of these newborns will become carriers of chronic HBV. About a quarter of them will subsequently develop cirrhosis or hepatocellular carcinoma. This perinatal infection can be prevented by neonatal immunity. This article and recommended for high-risk treatment of infants. About 90% of babies born to her have a perinatal infection if the HBsAg mother is also positive for hepatitis B e antigen (HBeAg). Mothers are HBeAg-negative or they have antibodies to HBeAg and their infants are less dangerous but can still be infected. Infected infants usually become HBsAg positive only a few weeks after birth. Although they are rare jaundice or acute hepatitis, elevated levels of aminotransferases are common. Because they are holding