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近年来肺癌发病率有增高趋势,但目前对肺癌诊断及治疗尚缺乏有效方法。杂交瘤技术产生的单克隆抗体具有纯度高、特异性强等优点。Sikora、Kasai和NCI的Minna实验室等都研制了针对不同组织类型的肺癌单克隆抗体。肺腺癌细胞株A_(549)免疫BALB/c小鼠后研制的HLC_3系列单克
In recent years, the incidence of lung cancer has increased, but there is still no effective method for the diagnosis and treatment of lung cancer. The monoclonal antibodies produced by hybridoma technology have the advantages of high purity and specificity. Sikora, Kasai, and NCI’s Minna Laboratories have developed monoclonal antibodies against lung cancer of different tissue types. BALB/c mice immunized with lung adenocarcinoma cell line A_(549) developed HLC_3 series