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目的:观察α1受体拮抗剂坦洛新联用氨酚双氢可待因治疗肾绞痛的临床疗效。方法:对临床确诊的82例急性肾绞痛患者随机分为观察组及对照组,观察组给予坦洛新0.2mg及氨酚双氢可待因0.5g口服,对照组给予度冷丁75mg及阿托品0.5mg肌肉注射。观察两组疗效及复发率。结果:观察组总有效率90.5%,对照组总有效率95.0%,两组差异无统计学意义。而观察组复发率低,副作用少。结论:坦洛新联用氨酚双氢可待因治疗肾绞痛疗效较度冷丁联用阿托品相似,且复发率低,副作用少,安全性好,用药方便,值得临床推广应用。
Objective: To observe the clinical efficacy of tamsulosin plus alpha1-adrenoceptor antagonist in the treatment of renal colic. Methods: A total of 82 patients with acute renal colic were randomly divided into observation group and control group. The observation group was given 0.2 mg tamsulosin and 0.5 g salmeterol hydrocodone 0.5 g orally, while the control group was given 75 mg atropine and atropine 0.5mg intramuscular injection. The curative effect and recurrence rate of the two groups were observed. Results: The total effective rate was 90.5% in the observation group and 95.0% in the control group, with no significant difference between the two groups. The observation group recurrence rate is low, fewer side effects. Conclusion: Tamsulosin combined with acetaminophen hydrocortisone for renal colic is more effective than atropine in the treatment of renal colic, with low recurrence rate, less side effects, good safety and convenient medication, which is worthy of clinical application.