应用流式细胞仪（ＦＡＣ４２０），分析经含不同浓度马氏钳蝎蝎毒（ＳｃｏｖｐｉｏｎＶｅｎｏｍＣｒｕｄｓ，ＳＶＣ）的培养基，培养人食管癌细胞株（Ｅｃａ１０９），观察蝎毒对人食管癌细胞株细胞周期的影响。结果：ＳＶＣ可使Ｅｃａ１０９细胞ＤＮＡ指数下降，引起细胞周期中Ｇ０／Ｇ１期细胞的积聚和Ｓ期细胞明显减少，导致Ｅｃａ１０９细胞的增殖指数降低。与对照组比差异均有显著性（Ｐ＜００５）。提示：ＳＶＣ可能抑制Ｅｃａ１０９细胞ＤＮＡ合成，起到抑制癌细胞增殖的作用。 Flow cytometry (FAC420) was used to analyze the culture medium containing different concentrations of ScovpionVenom Cruds (SVC) to culture human esophageal cancer cell lines (Eca109) and to observe the antiviral drugs against humans. The effect of cell cycle on esophageal cancer cell lines. RESULTS: SVC could decrease the DNA index of Eca109 cells, which caused the accumulation of cells in G0/G1 phase and the decrease of S phase cells in the cell cycle, leading to a decrease in the proliferation index of Eca109 cells. The difference from the control group was significant (P < 0.05). Hint: SVC may inhibit the DNA synthesis of Eca 109 cells and play a role in inhibiting the proliferation of cancer cells.