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选取2014年5月~2016年2月期间我院收治的144例老年2型糖尿病肾病合并高血压患者,随机分为观察组(n=72)和对照组(n=72)。对照组服用硝苯地平控释片,观察组联合缬沙坦。结果:治疗后,两组血压均降低,观察组低于对照组(P<0.05);对照组血尿素氮(BUN)、血肌酐(SCr)、尿白蛋白排泄率(UAER)无明显变化(P>0.05);观察组治疗后的BUN、UAER、SCr较治疗前降低(P<0.05)。结论:联合缬沙坦治疗更能改善老年2型糖尿病肾病合并高血压患者的肾功能和血压水平。
One hundred and forty-four elderly patients with type 2 diabetic nephropathy with hypertension who were admitted to our hospital from May 2014 to February 2016 were randomly divided into observation group (n = 72) and control group (n = 72). Control group taking nifedipine controlled release tablets, observation group combined with valsartan. Results: After treatment, the blood pressure in both groups decreased, and the observation group was lower than the control group (P <0.05). There was no significant change in the blood urea nitrogen (BUN), serum creatinine (SCr) and urinary albumin excretion rate P> 0.05). The BUN, UAER and SCr in observation group were lower than those before treatment (P <0.05). Conclusion: Combination valsartan treatment can improve the renal function and blood pressure of elderly patients with type 2 diabetic nephropathy complicated with hypertension.