用氧化丙烯与β-环糊精(简称CyD)缩合制备羟丙基β-CyD 有五种方法和条件。方法A:将61.7g NaOH 溶解于300ml 蒸馏水中,加入β-CyD 200g,50～60℃搅拌约30min 至结晶溶解。将瓶置于水浴中搅拌,滴加95ml 氧化丙烯,用于冰-丙酮冷凝器回流3h,得淡黄色澄明溶液,室温搅 There are five methods and conditions for preparing hydroxypropyl β-CyD by condensation of propylene oxide with β-cyclodextrin (referred to as CyD). Method A: Dissolve 61.7 g NaOH in 300 ml distilled water, add 200 g of β-CyD and stir at 50-60 ° C. for about 30 min until the crystals are dissolved. The bottle was placed in a water bath with stirring, dropping 95ml of propylene oxide for ice - acetone condenser reflux 3h, pale yellow clear solution, stirring at room temperature