痛风是由于尿酸结晶沉积在关节引起炎症、疼痛,甚至造成患者活动障碍的一组临床综合征。慢性心力衰竭患者经常伴随高尿酸血症,在这些患者中,痛风的处理是一个特殊的问题。由于心力衰竭患者对容量状态敏感和经常伴有慢性肾功能不全, 因而其痛风的治疗限制了非甾体类抗炎药和皮质类固醇激素的应用;同时,治疗高尿酸血症和痛风的药物与治疗心力衰竭的药物也存在相互影响。因此,现就慢性心力衰竭患者中高尿酸血症和痛风的处理作一综述。 Gout is a group of clinical syndromes caused by deposition of uric acid crystals in the joints that cause inflammation, pain, and even obstruction of the patient’s mobility. Patients with chronic heart failure are often associated with hyperuricemia and gout treatment is a particular problem in these patients. Treatment of gout restricts the use of NSAIDs and corticosteroids because of the capacity-state-sensitive and often associated with chronic renal insufficiency in patients with heart failure. In the meantime, therapies for hyperuricemia and gout are associated with Drugs that treat heart failure also interact. Therefore, the treatment of hyperuricemia and gout in chronic heart failure patients is now reviewed.