论文部分内容阅读
目的 探讨妊娠合并心脏病患者左室功能变化。方法 采用彩色多普勒超声心动图对 5 5例妊娠合并心脏病患者 ,于孕 2 8～ 32周进行左室功能测定 ,包括左室舒张末期内径 (LVIDd)、左室收缩末期内径 (LVIDs)、左室射血分数 (LVEF)等反映左室收缩功能的指标 ,以及二尖瓣下舒张早期充盈峰 (E)、舒张晚期充盈峰 (A)及其比值 (E/A)等反映左室舒张功能的指标。按NYHA心功能分级法 ,心功能Ⅰ～Ⅱ级 30例 ,Ⅲ～Ⅳ级 2 5例 ,并以15例非心脏病产妇做为对照。结果 三组孕妇的左室收缩功能无明显差异 (P >0 0 5 ) ,而心功能Ⅲ～Ⅳ级患者左室舒张功能显著低于Ⅰ～Ⅱ级患者及无心脏病对照组 (P <0 0 5 ,P <0 0 0 1)。结论 对NYHA心功能Ⅲ～Ⅳ级的妊娠合并心脏病患者 ,应注意其舒张功能的测定。
Objective To investigate the changes of left ventricular function in pregnancy complicated with heart disease. Methods Fifty-five patients with pregnancy complicated with heart disease underwent color Doppler echocardiography. Left ventricular function was measured at 28-32 weeks of pregnancy, including left ventricular end diastolic dimension (LVIDd), left ventricular end-systolic dimension (LVIDs) , Left ventricular ejection fraction (LVEF) and other parameters that reflect left ventricular systolic function, as well as early mitral diastolic filling peak (E), late diastolic filling peak (A) and its ratio (E / A) Diastolic function index. According to the NYHA functional classification, 30 cases of grade Ⅰ ~ Ⅱ and 25 cases of grade Ⅲ ~ Ⅳ were selected as control. Fifteen non-cardiac mothers were used as control. Results There was no significant difference in left ventricular systolic function between the three groups (P> 0.05), while LV diastolic function in patients with grade Ⅲ ~ Ⅳ cardiac function was significantly lower than that in patients with grade Ⅰ ~ Ⅱ and without heart disease (P <0 0 5, P <0 0 0 1). Conclusions NYHA functional class Ⅲ ~ Ⅳ pregnancy with heart disease should pay attention to the determination of diastolic function.