原发中枢神经系统淋巴瘤是一种较罕见的中枢神经系统恶性肿瘤,不向中枢神经系统轴以外播散,生物学行为具有侵袭性,病理形态存在异质性,临床无典型性,影像表现多样性,实验室检查无特异性,依靠病理免疫组化及分子生物学方可确诊。对手术切除分歧较大,虽然对放射及化学药物治疗敏感,但缺乏共识方案,较全身及其他部位淋巴瘤预后差。 Primary central nervous system lymphoma is a rare malignancy of the central nervous system that does not spread beyond the axis of the central nervous system. Its biological behavior is invasive, with heterogeneity of pathological forms, clinical manifestations, and imaging manifestations Diversity, laboratory tests without specificity, relying on pathological immunohistochemistry and molecular biology before diagnosis. The surgical resection of the larger differences, although sensitive to radiation and chemical therapy, but the lack of consensus programs, systemic and other parts of the lymphoma prognosis is poor.