While emerging data suggest nucleotide oligomerization domain receptor 1 (NOD1),a cytoplasmic patte recognition receptor,may play an important and complementary
Common y chain cytokines are important for immune memory formation.Among them,the role of IL-2 remains to be fully explored.It has been suggested that this cyto
The mechanisms underlying spatial and temporal control of cortical neurogenesis of the brain are largely elusive.Long non-coding RNAs (IncRNAs) have emerged as
SIRT7,a sirtuin family member implicated in aging and disease,is a regulator of metabolism and stress responses.It remains elusive how human somatic stem cell p
Cutaneous nociception is essential to prevent individuals from sustaining injuries.According to the conventional point of view,the responses to noxious stimuli
Innate lymphoid cells (ILCs) are defined as lymphocytes that lack RAG recombinase and do not express diverse antigen receptors;however,recent studies have revea
Immunotherapy has been applied successfully to treat B-cell lymphomas in preclinical models or clinical settings.However,immunotherapy resistance is a major cha
Inhibition of Mycobacterium tuberculosis (Mtb) cell wall assembly is an established strategy for anti-TB chemotherapy.Arabinosyltransferase EmbB,which catalyzes