论文部分内容阅读
视神经周围炎(OPN)是指涉及视神经鞘膜的一系列病理性炎症。OPN的经典三联征包括单侧视神经病变伴随疼痛和/或视盘水肿,此病症与其它视神经病变相似,导致诊断延迟和治疗欠佳。2016年1月,我们对发表于Medline和Ovid数据库的关键词为“视神经周围炎”的各种语言的文献进行了检索,共查找到60篇文献,发表于1956-2015年。两位作者(Tai ELM和Tevaraj JMP)分别对论文摘要进行了独立筛选,并筛选出相关文章。本次综述,我们强调OPN的特点,特别是OPN和视神经炎之间的临床差异。虽然大多数OPN的病例是特发性的,但仍需进行调查以排除特异性感染和继发性OPN的炎症原因。MRI是非常重要的检查方法,由于OPN视神经周围炎症的影像学诊断。糖皮质激素治疗可使症状与体征迅速好转,长期口服糖皮质激素并慢速递减可以降低复发的风险。
Optic nerve inflammation (OPN) refers to a series of pathological inflammation involving the optic nerve sheath. The classic triad of OPN includes unilateral optic neuropathy with pain and / or optic disc edema similar to other optic neuropathy resulting in delayed diagnosis and poor treatment. In January 2016, we searched the various languages published in the Medline and Ovid databases for key words “peri-optic inflammation” and found 60 articles published in 1956-2015. The authors (Tai ELM and Tevaraj JMP) separately screened abstracts and selected relevant articles. For this review, we highlight the features of OPN, particularly the clinical differences between OPN and optic neuritis. Although the majority of cases of OPN are idiopathic, investigations are still needed to rule out the causes of inflammation of specific infections and secondary OPN. MRI is a very important method of examination due to the imaging diagnosis of inflammation of the optic nerve around OPN. Glucocorticoid treatment can make the symptoms and signs of rapid improvement, long-term oral glucocorticoid and slow decline can reduce the risk of relapse.