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The authors assessed whether magnetoencephalography/magnetic source imaging (MEG/MSI) identified epileptogenic zones in patients with tuberous sclerosis complex (TSC). In six TSC children with focal seizures, ictal video-EEG predicted the region of resection with 56%sensitivity, 80%specificity, and 77%accuracy (p = 0.02), whereas interictal MEG/MSI fared better (100%, 94%, and 95%, respectively; p < 0.0001). Interictal MEG/MSI seems to identify epileptogenic zones more accurately in children with TSC and focal intractable epilepsy.
The authors assessed whether magnetoencephalography / magnetic source imaging (MEG / MSI) identified epileptogenic zones in patients with tuberous sclerosis complex (TSC). In six TSC children with focal seizures, ictal video-EEG predicted the region of resection with 56% sensitivity, 80 % specificity, and 77% accuracy (p = 0.02), Interictal MEG / MSI fared better (100%, 94%, and 95%, respectively; p <0.0001). Interictal MEG / MSI seems to identify epileptogenic zones more accurately in children with TSC and focal intractable epilepsy.