The present work is aimed at studying the mechanic properties of the extra-wide concrete self-anchored suspension bridge under static and dynamic vehicle loads. Based on the field test using 12 heavy trucks and finite element simulations, the static deformations of different components, stress increments and distributions of the girder, as well as the vibration characteristics and damping ratio of the Hunan Road Bridge were analyzed, which is the widest self-anchored suspension bridge in China at present. The dynamic responses were calculated using the Newmark-β integration method assisted by the simulation models of bridge and vehicles, the influences on the dynamic impact coefficient (DIC) brought by the vehicle parameters, girder width, eccentricity travel and deck flatness were also researched. The spatial effect of the girder is obvious due to the extra width, which performs as the stress increments distribute unevenly along the transverse direction, and the girder deflections and stress increments of the upper plate change as a V and M shape respectively under the symmetrical vehicle loads affected by the shear lag effect, cross slope and local effect of the wheels, the maximum of stress increments are located in the junctions with the inner webs. The obvious girder torsional deformation and the apparent unevenness of the hanger forces between the two cable planes under the eccentric vehicle loads, together with the mode shapes such as the girder transverse bending and torsion which appear relatively earlier, all reflect the weakened torsional rigidity of the extra-wide girder. The transverse displacements of towers are more obvious than the longitudinal ones. As for the influences on the DIC, the static effect of the heavier vehicles plays a major role when pass through with a higher speed and the changes of vehicle suspension stiffness generate greater impacts than the suspension damp. The values of DIC in the vehicle-running side during the eccentric travel, affected by the restricts from the static effects of the eccentric moving trucks, are significantly smaller than the vehicle-free side, the increase in the road roughness is the most sensitive one among the above influential factors. The results could provide references for the design, static and dynamic response analysis of the similar extra-wide suspension bridges.