如何预测出生前胎儿的性别,这是一个早就被人们重视的问题。为此,多年来从不同角度、用不同方法试图解决这个问题。目前应用羊水和绒毛膜细胞的X染色质和Y染色质预测胎儿的性别,已为国内外大量科学实践所证明,安全有效,准确率高。本文将着重介绍这方面的进展,以供参考。一、X染色质和Y染色质 X染色质是1949年Barr等首先在雌猫的神经细胞核内发现的,当时定名为核仁卫星。至1953年他们又提出:用检查性染色质的简单方法,作为诊断人类性发育缺陷患者的依据,故将核仁卫星改称为性染色 How to predict the gender of the fetus before birth is a problem that has long been valued by people. For this reason, from different perspectives over the years, they have used different methods to try to solve this problem. The current application of amniotic fluid and chorionic cells X chromatin and Y chromatin to predict the gender of the fetus has been proved for a large number of scientific and technological practice at home and abroad, safe and effective, high accuracy. This article will highlight the progress in this area for reference. First, X Chromatin and Y Chromatin X Chromatin was Barr in 1949 first found in the female cat’s nerve cell nucleus, was named the nucleolar satellite. By 1953 they proposed again: the simple method of examination of chromatin, as a basis for diagnosis of human sexual development defects, it renames nucleolar satellite sex dye