狼疮肾炎的病理分型是临床诊治及预后判断的基础。狼疮肾炎的治疗策略与进展更是建立在不断累积的循证医学证据之上。增生性狼疮肾炎因其相对较差的预后而更受关注,其治疗强调序贯使用诱导与维持治疗。经济条件许可,可考虑把MMF与环磷酰胺一样作为活动性狼疮肾炎诱导治疗的一线选择用药,而其他新型免疫制剂的疗效尚缺乏足够证据。维持治疗目前推荐硫唑嘌呤或MMF。部分难治性狼疮肾炎可以尝试其他治疗方法,但疗效都不确定。 Pathological classification of lupus nephritis is the basis of clinical diagnosis and prognosis. Lupus nephritis treatment strategies and progress is built on evidence-based medicine continues to accumulate. Prostatic hyperplasia lupus nephritis has drawn more attention for its relatively poor prognosis and its treatment emphasizes sequential induction and maintenance therapy. Economic conditions permit, may consider MMF and cyclophosphamide as active lupus nephritis induction therapy for first-line choice of medication, and the efficacy of other new immune agents is still not enough evidence. Maintenance therapy currently recommended azathioprine or MMF. Some refractory lupus nephritis can try other treatments, but the efficacy are not sure.