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大鼠中脑导水管周围灰质(PAG)向三又神经脊束核尾侧亚核(Sp 5 C)投射的起源细胞在其吻、中、尾三个部分的分布不同,且由尾段向吻段有从腹侧向背侧移行的趋势。尾段的HRP逆标细胞主要位于PAG的腹外侧区、内侧区腹侧部;中段的标记细胞较多,主要见于腹外侧区、背侧区和背外侧区腹侧部,尚可见一些顺行标记的终末;吻段的标记细胞主要位于背外侧区,在上丘深层、Cajal氏中介核、Darkschewitsch氏核内,也可见标记细胞。标记细胞和终末均主要位于注射侧的PAG内。PAG向Sp 5 C投射的5-羟色胺(5-HT)样神经元主要位于PAG的中、尾段的腹外侧区和内侧区腹侧部。中段的双标细胞占全部双标细胞数的57％,尾段占41％,吻段占2％。在背中缝核(DR)内,亦可见到一些双标细胞。PAG内的双标细胞占其HRP标记细胞总数的37％,但仅占5-HT样阳性细胞总数的4.5％。标记细胞主要为中型(20—30μm)梭形及三角形,小型(<20μm)梭形和大型(>30μm)多角形细胞较少见。
The distribution of the progenitor cells projected from PAG to Sp 5 C in the rat middle cerebral palsy was different in the three parts of their kiss, middle and tail, Kiss segment from the ventral to the dorsal line migration trend. The caudal section of HRP retrograde cells mainly located in the ventral side of the PAG, the ventral side of the medial region; there are more labeled cells in the middle section, mainly seen in the ventral side of the ventral, dorsal and dorsolateral regions, Labeled terminal; kissed segment marked cells are mainly located in the dorsal lateral zone, in the deep inferior meridian, Cajal’s intercalary nucleus, Darkschewitsch’s nucleus, also marked cells. Both the labeled cells and the terminal are predominantly located within the injection-side PAG. Serotonin (5-HT) -like neurons projected by PAG into Sp 5 C are located mainly in the ventral and medial regions of the medial and caudal segments of PAG. The middle double-labeled cells accounted for 57% of all double-labeled cells, the tail section accounted for 41% kiss 2%. In the dorsal raphe nucleus (DR), also see some double-labeled cells. Double-labeled cells in PAG account for 37% of the total number of HRP-labeled cells but only 4.5% of the total number of 5-HT-like positive cells. Marked cells are mainly medium (20-30μm) fusiform and triangular, small (<20μm) fusiform and large (> 30μm) polygonal cells are rare.