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目的:探讨院前早期用尿激酶(UK)对急性超早期脑梗塞临床疗效及其影响溶栓疗效的因素。方法:对发病6h内超早期急性脑梗塞患者73例,分为二组,其中UK溶栓组为治疗组,对照组给予胞二磷胆碱,观察及分析临床疗效。结果:治疗组35例中总有效率为91％,对照组38例中总有效率为78％,二组有明显差异(P<0.05)。结论:院前早期大剂量尿激酶溶栓能使神经功能缺损明显改善,是治愈急性脑梗塞最有效的方法之一。
Objective: To investigate the clinical effect of urokinase (UK) on acute ultra-early cerebral infarction in early prehospital period and its influencing factors on thrombolysis. Methods: 73 cases of acute early cerebral infarction within 6 hours after onset were divided into two groups, of which the UK thrombolysis group was the treatment group and the control group was given citicoline, and the clinical curative effect was observed and analyzed. Results: The total effective rate was 91% in the 35 cases in the treatment group and 78% in the control group, the difference was significant (P <0.05). Conclusion: Early prehospital administration of high-dose urokinase thrombolytic therapy can significantly improve neurological deficit, and is one of the most effective ways to cure acute cerebral infarction.